Drive to Middle Sespe Trailhead, 17.1 miles north of Ojai on Highway 33. The trailhead is on the right side of the highway . The trail crosses Sespe Creek and follows the old road. It then leaves the drainage and climbs over a steep bluff. Once you have reached the high point, you will drop down and cross Rock Creek. The trail parallels the Sespe until it joins the Gene Marshall-Piedra Blanca National Recreation Trail 22W03) . This junction is .8 miles from the Piedra Blanca trailhead.
The trail follows the north bank of Sespe Creek but climbs over a tall ridge to descend to and cross Rock Creek. It then passes on the north side of the river across from the old Herb Lathrop camp which later became the Circle B Ranch. At one time this ranch was a Boy Scout Camp but now is private property and called Rainbow Valley Ranch. Continuing down stream to a junction with the Gene Marshall National Recreation Trail then crossing the Sespe to end at Lion Camp. In the spring there is often good fishing in the Sespe between the mouth of Howard Creek and